Chinese scholars have developed world-class | gene editing _ gene editing technology news
Xinhua News Agency, Beijing, May 9-Roundup: Chinese scholars have developed world-class gene editing technology
Xinhua News Agency reporter Huang 堃
United Kingdom was recently reported in the journal Nature biotechnology, Chinese scientists invented a gene-editing technologies NgAgo-gDNA. Expert commentary, although this technology is still in its early stages, but its potential is expected to surpass recent is seen as the Nobel Prize of the United States CRISPR-Cas9 technology.
Gene editing was recently featured in the life sciences research, United States researchers developed CRISPR-Cas9 technology is the most hottest, based on ribonucleic acid (RNA) as a guiding tool, genes can be cut and edit operations. This technology can be used not only to explore the mysteries of life, there are many applications, such as modifying the genes to improve milk production in dairy cows, modify plant genes to improve resistance to insects, it can also be used in gene therapy research.
Led NgAgo-gDNA Han Chunyu, an associate professor of research and development of science and technology of Hebei University of technology told Xinhua said that this gene-editing technologies in Netherlands peer research on the basis of use of deoxyribonucleic acid (DNA) rather than ribonucleic acid as a guiding tool, some advantages. For example: limit on the edit object smaller, can edit any location within the genome; edited higher precision, avoids the previous techniques Miss phenomenon occurring in some cases.
The Executive Editor for the journal nature Nike·kanbeier commented: "while the technology is still in its infancy, but there are reasons to believe that it compared with the now widespread use of CRISPR-Cas9 technology has many advantages, particularly in terms of more precise gene-editing. ”
"Han Chunyu's work is international first-class technology forward," Director of the Peking University Department of science, biologist Professor Rao comments. He served as editor in Chief of science, new media of the intellectual journal article, introduced the academic details and value of this result.
After the publication of the results, Han Chunyu messages by international peers "bombing", we have asked the technical details. He said, the technology and CRISPR-Cas9 are technically have different characteristics, and if there was any shortage of the technology remains widely used peer to test.
Medical College in Tsinghua University Professor Lu Bai pointed out that NgAgo-gDNA technical intellectual property spring rains in the South team, and is still not seeing the competing, this is a big advantage. CRISPR-Cas9 inventor of the technology in the United States Chinese scientist Zhang feng and others at MIT, United States University of California zhennifu·daodena, who, because of the great technology in scientific and business prospects, both teams are the ownership of patent right for this technology to file a lawsuit.
"Our ownership of intellectual property rights, is not only conducive to China's life science community to use this technology, some big foreign companies may also take the initiative to pay requested technical authority," said Prof. Bai Lu.
Han Chunyu did not study overseas experience in world-class laboratories, the research results are not achieved. "Do the study mainly rely on people and equipment is secondary. "Han Chunyu, told reporters:" I think young researchers do not complain about the environment, but to fight for the environment, and do your own research, then we can wait until the day bear fruit. ”
"A lesser-known University, we train researchers to make the results, and the United States of the latest technology challenge, is a great thing," Prof. Bai Lu said. (End)
Responsible editor: Liu Debin SN222
Article keywords:Gene editing
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中国学者研发出国际一流基因编辑技术|基因编辑_新闻资讯
新华社北京5月9日电综述：中国学者研发出国际一流基因编辑技术
新华社记者黄堃
英国《自然·生物技术》杂志日前报告了中国科研人员发明的一种基因编辑技术NgAgo－gDNA。有专家评论，尽管这种技术尚处于初期阶段，但其潜力有望超过近来被看作诺贝尔奖热门的美国CRISPR－Cas9技术。
基因编辑是近来生命科学领域的热门研究方向，美国研究人员发明的CRISPR－Cas9技术最为炙手可热，它以核糖核酸(RNA)作为引导工 具，能对基因进行剪切和编辑操作。这项技术不仅可用于探索生命奥秘，还有许多应用前景，比如修改奶牛基因提高产奶量，修改植物基因提高抗虫性等，它还可以 用于基因疗法研究等。
领导NgAgo－gDNA技术研发的河北科技大学副教授韩春雨向新华社记者介绍说，这种基因编辑技术是在荷兰同行的研究基础上，使用脱氧核糖 核酸(DNA)而不是核糖核酸作为引导工具，取得一些优势。比如：编辑对象所受限制更小，能编辑基因组内任何位置；编辑精准度更高，能避免前一技术在某些 情况下出现的脱靶现象。
《自然》杂志执行主编尼克·坎贝尔评论说：“虽然这项新技术还处于初期，但有一些理由让我们相信它与现在普遍使用的CRISPR－Cas9技术相比有多种优势，特别是在更精准的基因编辑方面。”
“韩春雨的工作是国际一流的技术推进，”北京大学理学部主任、生物学家饶毅教授如此评论。他担任主编的科学类新媒体《知识分子》刊文，介绍了这项成果的学术细节和价值。
这项成果发表后，韩春雨受到了国际同行的邮件“轰炸”，大家纷纷询问技术细节。他说，这项技术与 CRISPR－Cas9在技术上各有特点，而该技术是否有什么不足，还有待同行广泛使用来检验。
清华大学医学院教授鲁白指出，NgAgo－gDNA技术的知识产权掌握在韩春雨团队手中，目前还没有看到有人与之竞争，这又是一大优势。而 CRISPR－Cas9技术的发明者中有美国麻省理工学院的华人科学家张峰等人，也有美国加利福尼亚大学的珍妮弗·道德纳等人，由于该技术在科学上和商业 上的巨大前景，双方团队正为这一技术的专利权归属打官司。
“我们自己掌握了知识产权，不仅有利于中国生命科学界使用这项技术，一些国外的大公司也可能会主动来付费要求得到技术授权，”鲁白说。
韩春雨并没有海外求学经历，研究成果也并非在国际一流的实验室中取得。“做研究主要还是靠人，设备环境只是第二位的。”韩春雨对记者表示：“我认为青年科研人员不要抱怨环境，而是要争取环境，做自己喜欢的研究，就自然能等到结出成果的那一天。”
“在一所不太有名的大学，我们自己培养出的科研人员也能做出这样的成果，能够和美国的最新技术叫板，是一件了不起的事情，”鲁白评价说。(完)
责任编辑：刘德宾 SN222
文章关键词： 基因编辑
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